NP1 ACTIVITY REGULATING ELEMENTS USEFUL FOR THE PRODUCTION OF DRUGS FOR THE TREATMENT OR PREVENTION OF HUMAN NEURODEGENERATIVE DISEASES, RESULTING DRUGS AND USE THEREOF

摘要

The invention relates to a series of compounds useful for the production of drugs or pharmaceutical compositions for the treatment or prevention of human neurological diseases, preferably neurodegenerative diseases, which inhibit the activity of the human NP1 protein which acts as an inducer of neurodegeneration and neural apoptosis. Said compounds include iRNA inhibitors of the gene expression of the NP1 gene and specific antibodies of the human NP1 protein, as well as peptides derived from same, which can be used in passive and active immunisation methods respectively against said diseases.