STABILIZED LIQUID AND LYOPHILIZED ADAMTS13 FORMULATIONS
摘要
<p>The present invention relates to formulations of ADAMTS13 with enhanced or desirable properties. As such, the invention provides liquid and lyophilized formulations of ADAMTS13 that are suitable for pharmaceutical administration. Among other aspects, the present invention also provides methods of treating various diseases and conditions related to VWF and/or ADAMTS13 dysfunction in a subject. Also provided herein are kits comprising ADAMTS13 formulations useful for the treatment of various diseases and conditions.</p>
申请公布号
WO2011035335(A2)
申请公布日期
2011.03.24
申请号
WO2010US49723
申请日期
2010.09.21
申请人
BAXTER INTERNATIONAL INC.;BAXTER HEALTHCARE S.A.;MATTHIESSEN, H., PETER;TURECEK, PETER, L.;SCHWARZ, HANS-PETER