MODIFIED ERYTHROPOIETIN TO WHICH WATER-SOLUBLE LONG-CHAIN MOLECULE IS ADDED

摘要

Disclosed is a pharmaceutical composition which contains erythropoietin as an active ingredient and exerts a hematopoietic effect that lasts for 7 days or more when administered to a human and/or an animal. Specifically disclosed are: a pharmaceutical composition that contains erythropoietin, to which two or more water-soluble long-chain molecules are added, in an amount of not less than 50% of the total erythropoietin; a pharmaceutical composition that contains erythropoietin to which a water-soluble long-chain molecule is added, said water-soluble long-chain molecule having a molecular weight of not less than 30 kDa; and a pharmaceutical composition that contains erythropoietin to which a water-soluble long-chain molecule is added, said water-soluble long-chain molecule having a branched chain.