发明名称 |
HBV EPITOPE REACTIVE EXOGENOUS T CELL RECEPTOR (TCR) AND USES THEREOF |
摘要 |
There is provided at least one isolated cell comprising at least one HBV epitope-reactive exogenous T cell receptor and/or fragment thereof, and methods for producing them. In particular, there is provided polynucleotides, constructs and vectors encoding at least one HBV epitope-reactive exogenous T cell receptor for use in the treatment of Hepatitis B Virus (HBV) and Hepatocellular Carcinoma (HCC). The invention further provides kits and methods of detection of HBV and HCC.
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申请公布号 |
US2011070208(A1) |
申请公布日期 |
2011.03.24 |
申请号 |
US20090991904 |
申请日期 |
2009.05.07 |
申请人 |
AGENCY FOR SCIENCE, TECHNOLOGY AND RESEARCH |
发明人 |
BERTOLETTI ANTONIO;GEHRING ADAM |
分类号 |
A61K35/12;A61P31/14;A61P35/00;C07H21/04;C07K1/00;C07K7/06;C07K14/00;C12N5/071;G01N33/48 |
主分类号 |
A61K35/12 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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