发明名称 |
NOVEL GAMMA-SECRETASE INHIBITOR |
摘要 |
It is intended to provide a novel compound that has an excellent γ-secretase inhibitory effect and specifically inhibits A&bgr; production. The present invention provides a compound of the following formula (1) or a pharmaceutically acceptable salt thereof: wherein R1 represents a linear or branched alkyl group having 1 to 4 carbon atoms or a phenyl group; R2 represents a linear or branched alkyl group having 1 to 4 carbon atoms which may be substituted by one or more phenyl or halogenophenyl groups; R3 represents a linear or branched alkyl group having 1 to 4 carbon atoms which may be substituted by one or more hydroxyl groups; R4 represents a linear or branched alkyl group having 1 to 4 carbon atoms; and the symbol “*” represents a chiral center.
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申请公布号 |
US2011071224(A1) |
申请公布日期 |
2011.03.24 |
申请号 |
US20080672326 |
申请日期 |
2008.07.01 |
申请人 |
KABUSHIKI KAISHA YAKULT HONSHA |
发明人 |
ABE ATSUHIRO;SHIMIZU HIDEAKI;SAWADA SEIGO;KODAIRA HIROSHI |
分类号 |
A61K31/198;A61P25/28;C07C229/28 |
主分类号 |
A61K31/198 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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