| 发明名称 |
CYTOTOXIC ANTI-LAG-3 MONOCLONAL ANTIBODY AND ITS USE IN THE TREATMENT OR PREVENTION OF ORGAN TRANSPLANT REJECTION AND AUTOIMMUNE DISEASE |
| 摘要 |
Cytotoxic anti-LAG-3 monoclonal antibodies or fragments thereof causing depletion of LAG-3+ activated T cells are described, as are related pharmaceuticals and methods of treating. Also described are related nucleic acid and protein sequences.
|
| 申请公布号 |
US2011070238(A1) |
申请公布日期 |
2011.03.24 |
| 申请号 |
US20100823795 |
申请日期 |
2010.06.25 |
| 申请人 |
IMMUTEP PARC CLUB ORSAY;INSERM - INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE |
发明人 |
TRIEBEL FREDERIC;VANHOVE BERNARD;HAUDEBOURG THOMAS |
| 分类号 |
A61K39/395;A61P7/06;A61P37/00;A61P37/06;C07H21/04;C07K16/00;C07K16/18;C12Q1/02;G01N33/53 |
主分类号 |
A61K39/395 |
| 代理机构 |
|
代理人 |
|
| 主权项 |
|
| 地址 |
|
