Disclosed herein is a gene that can be included in immunogenic compositions specific for pathogenic E. coli strains. The gene is from uropathogenic strains but is absent from non-pathogenic strains, and its encoded protein has cellular locations which render it accessible to the immune system.
申请公布号
EP2298795(A1)
申请公布日期
2011.03.23
申请号
EP20100180455
申请日期
2006.02.17
申请人
NOVARTIS VACCINES AND DIAGNOSTICS, INC.
发明人
PIZZA, MARIAGRAZIA;SERINO, LAURA;BERLANDA SCORZA, FRANCESCO;FONTANA, MARIA RITA;GOMES MORIEL, DANILO