发明名称 |
5-membered heterocycle-based P38 kinase inhibitors |
摘要 |
Provided are 5-membered heterocycle-based p38 kinase inhibitors. Further provided are pyrazole and imidazole-based p38 kinase, including p38± and p38² kinase, inhibitors. Pharmaceutical composititons coataining the compounds are also provided. Methods of use of the compounds and compositions are also provided, including methods of treatment, prevention, or amelioration of one or more symptoms of p38 Kinase mediated diseases and disorders, including, but not limited to, inflammatory diseases and disorders.
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申请公布号 |
EP2298743(A1) |
申请公布日期 |
2011.03.23 |
申请号 |
EP20100164367 |
申请日期 |
2004.06.24 |
申请人 |
NOVARTIS AG |
发明人 |
FRYSZMAN, OLGA M.;LANG, HENGYUAN;LAN, JIONG;CHANG, EDCON;FANG, YUNFENG |
分类号 |
C07D231/38;A61K31/415;A61P29/00;C07D231/44;C07D231/52;C07D233/88;C07D401/06;C07D401/10;C07D401/12;C07D403/10;C07D403/12;C07D405/10;C07D413/10;C07D413/12 |
主分类号 |
C07D231/38 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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