发明名称 |
DIFFERENTIATION OF PLURIPOTENT STEM CELLS |
摘要 |
The present invention is directed to methods to differentiate pluripotent stem cells. In particular, the present invention is directed to methods and compositions to differentiate pluripotent stem cells into cells expressing markers characteristic of the definitive endoderm lineage comprising culturing the pluripotent stem cells in medium comprising a sufficient amount of GDF-8 to cause the differentiation of the pluripotent stem cells into cells expressing markers characteristic of the definitive endoderm lineage. |
申请公布号 |
KR20110029155(A) |
申请公布日期 |
2011.03.22 |
申请号 |
KR20117001981 |
申请日期 |
2009.06.30 |
申请人 |
CENTOCOR ORTHO BIOTECH INC. |
发明人 |
LIU JIA JIAN;DAVIS JANET;PARMENTER CHRISTINE;BONNET PASCAL GHISLAIN ANDREE |
分类号 |
C12N5/071;C07K14/475;C12N5/02;C12N5/0735 |
主分类号 |
C12N5/071 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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