NOVEL COMPOUNDS, ISOMER THEREOF, OR PHARMACEUTICALLY ACCEPTABLE SALTS THEREOF AS VANILLOID RECEPTOR ANTAGONIST AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME

摘要

PURPOSE: A compound is provided to treat heart diseases, pain, and hair growth-associated diseases. CONSTITUTION: A pharmaceutical composition for preventing and treating pharmacological stimulation and/or abnormal expression of vaniloid receptor 1(VR1) contains a compound of chemical formula I, II, III, or IV, isomer thereof, or pharmaceutically acceptable salt and pharmaceutically acceptable carrier. The pharmaceutical composition is applied to rat, mouse, livestock, and human. The pharmaceutical composition is used by rectal, intravenous, intramuscular, or subcutaneous administration.