发明名称 DERIVATIVES OF 5-(PYRIDIN-3-YL)-1-AZABICYCLO[3.2.1]OCTANE, THEIR PREPARATION AND THEIR THERAPEUTIC APPLICATION
摘要 The invention relates to compounds having general formula (I), (see formula I) wherein R denotes a halogen atom, a phenyl group which is substituted by one or more groups selected from among halogen atoms and the (C1-C6) alkyl, (C1-C6) alcoxy, nitro, amino, trifluoromethyl, cyano, hydroxy, acetyl or methylenedioxy groups, a pyridinyl group, a thienyl group, an indolyl group, or a pyrimidinyl group which is optionally substituted by one or more (C1-C6) alcoxy groups. Moreover, among the two carbon-carbon bonds denoted by (see above formula) one is simple and the other can be simple or double. The inventive compounds are nicotinic receptor ligands.
申请公布号 CA2471628(C) 申请公布日期 2011.03.22
申请号 CA20032471628 申请日期 2003.01.03
申请人 SANOFI-SYNTHELABO 发明人 GALLI, FREDERIC;LECLERC, ODILE;LOCHEAD, ALISTAIR;NEDELEC, ALAIN
分类号 C07D471/18;A61K31/437;A61K31/439;A61K31/444;A61K31/4545;A61K31/46;A61K31/4709;A61K31/506;A61K31/5377;A61K31/55;A61P25/00;A61P25/14;A61P25/16;A61P25/18;A61P25/22;A61P25/24;A61P25/28;A61P25/30;C07D;C07D209/00;C07D221/00;C07D471/08 主分类号 C07D471/18
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