发明名称 |
Shc protein-related methods and compositions for the prognosis of breast, prostate and ovarian cancer |
摘要 |
This invention provides methods for determining whether a breast, prostate or ovarian tumor or tumor cell is aggressive, based on the quantitative measurement of p66-Shc and phosphorylated Shc. This invention also provides related methods of determining the likelihood of tumor recurrence. This invention further provides a method for determining whether a tumor can be successfully treated using a tyrosine kinase inhibitor. Finally, this invention provides antibodies and kits for practicing the instant methods.
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申请公布号 |
US7910314(B2) |
申请公布日期 |
2011.03.22 |
申请号 |
US20030376538 |
申请日期 |
2003.02.28 |
申请人 |
ROGER WILLIAMS HOSPITAL |
发明人 |
FRACKELTON, JR. A. RAYMOND;DAVOL PAMELA A. |
分类号 |
G01N33/48;G01N33/53;A61P35/04;C07K16/18;C12N5/10;C12N15/02;C12P21/08;C12Q1/02;C12Q1/68;G01N33/543;G01N33/574 |
主分类号 |
G01N33/48 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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