发明名称 PHOSPHORAMIDATE ALKYLATOR PRODRUG
摘要 FIELD: chemistry. ^ SUBSTANCE: invention relates to phosphoramidate alkylator prodrugs which can be used to treat cancer separately or combined with other anti-tumour agents, having formula: , where each X4 denotes Cl or Br. ^ EFFECT: obtaining novel compounds, having antiproliferative activity and pharmaceutical compositions based on said compositions. ^ 9 cl, 7 dwg, 56 ex, 43 tbl
申请公布号 RU2414475(C2) 申请公布日期 2011.03.20
申请号 RU20080103195 申请日期 2006.06.29
申请人 TRESHOLD FARMAS'JUTIKALZ, INK. 发明人 MATTEUCHCHI MARK;DUAN' TSZJAN'-SIN';TSZJAO KHAJLUN;KAJZERMAN DZHEKOB;AMMONS STIV
分类号 A61K31/664;A61P35/00;C07F9/24 主分类号 A61K31/664
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