发明名称 QUINAZOLINE DERIVATIVES EXHIBITING TYROSINE KINASE INHIBITING ACTIVITY
摘要 FIELD: medicine, pharmaceutics. ^ SUBSTANCE: invention refers to a new compound presented by general formula (I) where values of Rx, R3, R4, X and A substitutes are described in the patent claim, inhibiting tyrosine kinase of EGF receptor and HER2 tyrosine kinase, as well as to using the compound of formula (I) and pharmaceutical composition containing this compound or its pharmaceutically acceptable salt. ^ EFFECT: preparation of the tyrosine kinase inhibiting compound. ^ 14 cl, 19 ex, 53 tbl
申请公布号 RU2414457(C2) 申请公布日期 2011.03.20
申请号 RU20070135023 申请日期 2006.02.22
申请人 SIONOGI EHND KO., LTD. 发明人 KUME MASAKHARU;MATSUO KENDZI;OMORI NAOKI;TAKAJAMA MASAMI;OMORI AJKO;EHNDO TAKESI
分类号 A61K31/517;A61K31/5375;A61K31/5377;A61P35/00;C07D239/34;C07D239/94;C07D401/12;C07D405/06 主分类号 A61K31/517
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