| 发明名称 |
DEPLETING IMMUNOSUPPRESSIVE MONOCYTES WITHIN A MAMMAL |
| 摘要 |
This document provides methods and materials involved in depleting immunosuppressive monocytes (e.g., CD14+/DR- or CD14+/DRlow monocytes) within a mammal. For example, methods and materials involved in using a CD2 binding molecule (e.g., alefacept) to deplete immunosuppressive monocytes within a mammal (e.g., a human) are provided. |
| 申请公布号 |
WO2011031676(A2) |
申请公布日期 |
2011.03.17 |
| 申请号 |
WO2010US48002 |
申请日期 |
2010.09.07 |
| 申请人 |
MAYO FOUNDATION FOR MEDICAL EDUCATION AND RESEARCH;WILCOX, RYAN A.;WITZIG, THOMAS E. |
发明人 |
WILCOX, RYAN A.;WITZIG, THOMAS E. |
| 分类号 |
A61K39/395;A61K38/17;A61P35/00;C12N5/071;C12N5/078 |
主分类号 |
A61K39/395 |
| 代理机构 |
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代理人 |
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| 主权项 |
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| 地址 |
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