PROCESS FOR THE PRODUCTION OF ARTEMISININ INTERMEDIATES
摘要
This application relates to a process for the production of (2R)-dihydroartemisinic acid or (2R)-dihydroartemisinic acid esters from artemisinic acid or artemisinic acid esters, respectively, by diimine hydrogenation of the exocyclic CC-double bond, and use of said process in the production of the antimalarial drug artemisinin.
申请公布号
WO2011030223(A2)
申请公布日期
2011.03.17
申请号
WO2010IB02566
申请日期
2010.09.10
申请人
SANOFI-AVENTIS;KRAFT, VOLKER;KRETZSCHMAR, GERHARD;ROSSEN, KAI