发明名称 |
METHODS OF DIAGNOSING AMYOTROPHIC LATERAL SCLEROSIS (ALS) |
摘要 |
<p>A method of diagnosing amyotrophic lateral sclerosis (ALS) in a subject in need thereof is provided. The method comprising determining in cells of the subject at least one alteration in a sequence or expression level of Cytoplasmic FMR Interacting Protein (CyFIP2; Accession AF160973) and/or Retinoblastoma Binding Protein 9 (RbBP9; Accession AF039564), wherein an altered sequence or expression of the sequence or expression level of the CyFIP2; Accession AF160973) or Retinoblastoma Binding Protein 9 (RbBP9; Accession AF039564) as compared to a control reference sample from a non-ALS subject, is indicative of ALS. The present teachings may be implemented in screening for novel anti-ALS medicaments and for treating ALS.</p> |
申请公布号 |
WO2011030336(A1) |
申请公布日期 |
2011.03.17 |
申请号 |
WO2010IL00732 |
申请日期 |
2010.09.06 |
申请人 |
RAMOT AT TEL-AVIV UNIVERSITY LTD.;WEIL, MIGUEL ENRIQUE;RECHAVI, GIDEON |
发明人 |
WEIL, MIGUEL ENRIQUE;RECHAVI, GIDEON |
分类号 |
C12Q1/68 |
主分类号 |
C12Q1/68 |
代理机构 |
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代理人 |
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地址 |
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