发明名称 Nogo Receptor Binding Small Molecules to Promote Axonal Growth
摘要 The present invention provides a method for identifying compounds which modulate the interaction of Nogo and Nogo receptor (NgR). The present invention also provides compounds that modulate the interaction of Nogo and Nogo receptor (NgR), the use of such compounds and compositions in the treatment or amelioration of conditions diseases or disorders, such as spinal cord injury, traumatic brain injury, stroke, multiple sclerosis, ALS, Huntington's disease, Alzheimer's disease, Parkinson's disease, epilepsy, Schizophrenia or schizoaffective disorders.
申请公布号 US2011065715(A1) 申请公布日期 2011.03.17
申请号 US20080745150 申请日期 2008.11.26
申请人 YALE UNIVERSITY 发明人 STRITTMATTER STEPHEN M.;GUNTHER ERIK
分类号 A61K31/4985;A61K31/135;A61K31/275;A61K31/343;A61K31/35;A61K31/404;A61K31/428;A61K31/47;A61K31/519;A61P25/00;C12N5/079;C40B30/04;G01N33/53 主分类号 A61K31/4985
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