发明名称 |
VIRAL ADJUVANTS |
摘要 |
The present invention provides viral adjuvants for enhancing an immune response to an immunogen. In particular embodiments, the viral adjuvant is an alphavirus adjuvant or a Venezuelan Equine Encephalitis viral adjuvant. Also provided are compositions comprising the viral adjuvant and an immunogen, and pharmaceutical formulations comprising the viral adjuvant or compositions of the invention in a pharmaceutically acceptable carrier. Further provided are methods of producing an immune response against an immunogen in a subject comprising administering the immunogen and a viral adjuvant of the invention to the subject.
|
申请公布号 |
US2011064772(A1) |
申请公布日期 |
2011.03.17 |
申请号 |
US20100954021 |
申请日期 |
2010.11.24 |
申请人 |
UNIVERSITY OF NORTH CAROLINA AT CHAPEL HILL |
发明人 |
JOHNSTON ROBERT E.;THOMPSON JOSEPH M. |
分类号 |
A61K39/39;A61P31/00;C07H21/02;C12N5/0783;C12P19/34 |
主分类号 |
A61K39/39 |
代理机构 |
|
代理人 |
|
主权项 |
|
地址 |
|