发明名称 |
Identification of discriminant proteins through antibody profiling, methods and apparatus for identifying an individual |
摘要 |
A method for determining a plurality of proteins for discriminating and positively identifying an individual based from a biological sample. The method may include profiling a biological sample from a plurality of individuals against a protein array including a plurality of proteins. The protein array may include proteins attached to a support in a preselected pattern such that locations of the proteins are known. The biological sample may be contacted with the protein array such that a portion of antibodies in the biological sample reacts with and binds to the proteins forming immune complexes. A statistical analysis method, such as discriminant analysis, may be performed to determine discriminating proteins for distinguishing individuals. Proteins of interest may be used to form a protein array. Such a protein array may be used, for example, to compare a forensic sample from an unknown source with a sample from a known source.
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申请公布号 |
US2011065594(A1) |
申请公布日期 |
2011.03.17 |
申请号 |
US20090586109 |
申请日期 |
2009.09.17 |
申请人 |
BATTELLE ENERGY ALLIANCE, LLC |
发明人 |
THOMPSON VICKI S.;LACEY JEFFREY A.;GENTILLON CYNTHIA A.;APEL WILLIAM A. |
分类号 |
C40B30/04;C40B40/10 |
主分类号 |
C40B30/04 |
代理机构 |
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代理人 |
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地址 |
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