| 摘要 |
When an antigen present at lesion sites is detected using a compound containing a single-chain antibody moiety, the single-chain antibody moiety binds to the antigen present at sites other than lesion sites. As a result, the detection of the lesion sites with high sensitivity and high contrast is difficult, and a compound solving this problem is demanded. The present invention provides a compound including a polymer represented by general formula (1): L-Y-A  (1) wherein, A is a single-chain antibody moiety, which is a polypeptide including an antigen-binding site; L is a linker moiety, which is a polypeptide including a protease cleavage site; Y is a peptide moiety, which including 0 or more amino acids connecting the linker moiety L with the single-chain antibody moiety A; and the linker moiety L binds to an N terminus of the peptide moiety Y or an N terminus of the single-chain antibody moeity A.
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