发明名称 THERAPEUTIC PIPERAZINES
摘要 The invention includes a compound of formula I: wherein R1, Y, A, n, R4 and Z have any of the values described herein, as well as salts of such compounds, compositions comprising such compounds, and therapeutic methods that comprise the administration of such compounds. The compounds are inhibitors of PDE4 function and are useful for improving cognitive function and/or treating cognitive disorders or impairment, traumatic and/or ischemic injuries of the central and peripheral nervous system and/or psychiatric disorders in animals, especially humans.
申请公布号 US2011065691(A1) 申请公布日期 2011.03.17
申请号 US20100887920 申请日期 2010.09.22
申请人 发明人 KAPLAN ALAN P.;KEENAN TERENCE P.;WEINHOUSE MICHAEL I.;WILSON MARK E.;LINDSTROM ANDREW K.;RIPKA WILLIAM C.;CHEN MI
分类号 A61K31/551;A61K31/495;A61K31/496;A61K31/5377;A61P25/00;A61P25/28;C07D241/04;C07D243/08;C07D401/06;C07D403/04;C07D403/06;C07D413/06;C07D413/14;C07D417/06;C12N5/07 主分类号 A61K31/551
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