发明名称 |
TREATMENT OF 'IQ MOTIF CONTAINING GTPASE ACTIVATING PROTEIN' (IQGAP) RELATED DISEASES BY INHIBITION OF NATURAL ANTISENSE TRANSCRIPT TO IQGAP |
摘要 |
<p>The present invention relates to antisense oligonucleotides that modulate the expression of and/or function of 'IQ motif containing GTPase activating protein' (IQGAP), in particular, by targeting natural antisense polynucleotides of 'IQ motif containing GTPase activating protein' (IQGAP). The invention also relates to the identification of these antisense oligonucleotides and their use in treating diseases and disorders associated with the expression of IQGAP.</p> |
申请公布号 |
WO2011031482(A2) |
申请公布日期 |
2011.03.17 |
申请号 |
WO2010US46642 |
申请日期 |
2010.08.25 |
申请人 |
CURNA, INC.;COLLARD, JOSEPH;KHORKOVA SHERMAN, OLGA;COITO, CARLOS |
发明人 |
COLLARD, JOSEPH;KHORKOVA SHERMAN, OLGA;COITO, CARLOS |
分类号 |
C12N15/113;A61K31/7088;A61K48/00;C12N15/52;C12N15/63 |
主分类号 |
C12N15/113 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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