| 发明名称 |
MODULATION OF HUNTINGTIN EXPRESSION |
| 摘要 |
<p>Provided herein are methods, compounds, and compositions for reducing expression of huntingtin mRNA and protein in an animal. Such methods, compounds, and compositions are useful to treat, prevent, delay, or ameliorate Huntington's disease, or a symptom thereof.</p> |
| 申请公布号 |
CA2773886(A1) |
申请公布日期 |
2011.03.17 |
| 申请号 |
CA20102773886 |
申请日期 |
2010.09.10 |
| 申请人 |
ISIS PHARMACEUTICALS, INC.;GENZYME CORPORATION |
发明人 |
HUNG, GENE;BENNETT, C. FRANK;FREIER, SUSAN M.;KORDASIEWICZ, HOLLY;STANEK, LISA;CLEVELAND, DON W.;CHENG, SENG H.;SHIHABUDDIN, LAMYA |
| 分类号 |
C12N15/113;C07H21/04;C07K14/47 |
主分类号 |
C12N15/113 |
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