| 摘要 |
<p><P>PROBLEM TO BE SOLVED: To provide a method for screening the mutation of the gene of familial aortic aneurysm, to provide a method for detecting familial aortic aneurysm on the basis of the mutation of the gene, and to provide a kit for detecting the familial aortic aneurysm. <P>SOLUTION: There is provided the method for comprehensively detecting the mutation of the triple helix domain of type 3 procollagen (COL3A1) gene which is a gene causing familial aortic aneurysm, the mutation of domains except the triple helix domain of the Col3A1 gene, the mutation of transforming growth factor beta receptor 1 (TGFBR1) gene or the mutation of transforming growth factor beta receptor 2 (TGFBR2) gene with a primer pair capable of amplifying the exon fragment of the gene. <P>COPYRIGHT: (C)2011,JPO&INPIT</p> |
