发明名称 |
EXTENDED RELEASE FORMULATION OF LEVETIRACETAM |
摘要 |
The present invention relates to extended release pharmaceutical compositions of Levetiracetam and processes for preparing the same. The extended release tablet of Levetiracetam is with a core comprising of Levetiracetam and water dispersible rate controlling polymer, and the tablet core is optionally functional coated comprising a combination of water non-dispersible and/or water dispersible polymer. It provides extended therapeutically effective plasma levels over a twenty four hour period with diminished incidences of neuropsychiatric adverse events by eliminating the troughs and peaks of drug concentration in a patient's blood plasma. The composition also exhibits no food effect.
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申请公布号 |
US2011064808(A1) |
申请公布日期 |
2011.03.17 |
申请号 |
US20100944936 |
申请日期 |
2010.11.12 |
申请人 |
UCB PHARMA S.A. |
发明人 |
KSHIRSAGAR RAJESH;RAO ASHWIN;MALAVIYA NILESH;JINTURKAR KAUSTUBH |
分类号 |
A61K9/28;A61K9/36;A61K31/4015;A61P25/08 |
主分类号 |
A61K9/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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