发明名称 |
A NOVEL PROTEIN DELIVERY SYSTEM TO GENERATE INDUCED PLURIPOTENT STEM (IPS) CELLS OR TISSUE-SPECIFIC CELLS |
摘要 |
<p>A novel protein delivery system to generate induced pluripotent stem (iPS) cells is described. The delivery system comprises a construct with a receptor binding domain that recognizes a receptor in a somatic cell, a translocation domain that allows the transfer of an inducer into the cytosolic space, and a cargo bearing domain to which the inducer is attached and facilitates transfer of the inducer into the cell.</p> |
申请公布号 |
CA2772400(A1) |
申请公布日期 |
2011.03.17 |
申请号 |
CA20102772400 |
申请日期 |
2010.08.27 |
申请人 |
SYNAPTIC RESEARCH, LLC |
发明人 |
CHANG, YUNG-NIEN;OYLER, GEORGE A. |
分类号 |
C12N15/85;C12N5/071;C12N5/10;C12N15/31 |
主分类号 |
C12N15/85 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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