发明名称 |
EXTRACELLULAR TARGETED DRUG CONJUGATES |
摘要 |
The present invention relates to, inter alia, extracellular drug conjugates (EDC) in which an antibody or other targeting agent (e.g. a targeting moiety) is linked to a drug through a linker (e.g. a non-cleavable linker). These conjugates are useful in the treatment of disease and/or as a tool in the evaluation of biological systems. |
申请公布号 |
CA2809819(A1) |
申请公布日期 |
2011.03.17 |
申请号 |
CA20102809819 |
申请日期 |
2010.09.09 |
申请人 |
CENTROSE, LLC |
发明人 |
PRUDENT, JAMES R.;THORSON, JON S.;BOLLETTIERI, JILL HUTCHINSON;HUTCHINSON, CHARLES B. |
分类号 |
C07K16/28;A61K47/48;C07K17/08 |
主分类号 |
C07K16/28 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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