| 发明名称 |
COMPOSITIONS AND METHODS FOR TREATMENT OF LEUKEMIA |
| 摘要 |
The invention relates generally to effective treatment leukemia. In particular, the present invention provides compositions and methods to inhibit the interaction of menin with MLL and MLL-fusion oncoproteins, and well as systems and methods to screen for such compositions.
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| 申请公布号 |
US2011065690(A1) |
申请公布日期 |
2011.03.17 |
| 申请号 |
US20100875968 |
申请日期 |
2010.09.03 |
| 申请人 |
THE REGENTS OF THE UNIVERSITY OF MICHIGAN;UNIVERSITY OF VIRGINIA PATENT FOUNDATION |
发明人 |
GREMBECKA JOLANTA;CIERPICKI TOMASZ;HESS JAY |
| 分类号 |
A61K31/519;A61K31/5377;A61K31/551;A61P35/04;C07D243/38;C07D401/04;C07D405/10;C07D491/048;C07D495/04;C12N5/02 |
主分类号 |
A61K31/519 |
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