| 发明名称 |
THERAPY WITH A CHIMERIC MOLECULE AND A PRO-APOPTOTIC AGENT |
| 摘要 |
<p>The present invention provides compositions comprising a chimeric molecule comprising a cytotoxin that inhibits protein synthesis and an agent that inactivates an anti-apoptotic BCL-2 family member protein and methods of inhibiting the growth of or promoting the apoptosis of an aberrantly proliferating cell population by co-administering the chimeric molecule and the agent that inactivates an anti-apoptotic BCL-2 family member protein.</p> |
| 申请公布号 |
WO2011031441(A1) |
申请公布日期 |
2011.03.17 |
| 申请号 |
WO2010US46382 |
申请日期 |
2010.08.23 |
| 申请人 |
THE GOVERNMENT OF THE UNITED STATES OF AMERICA ASREPRESENTED BY THE SECRETARY OF THE DEPARTMENT OFHEALTH AND HUMAN SERVICES;FITZGERALD, DAVID, J. |
发明人 |
FITZGERALD, DAVID, J. |
| 分类号 |
A61K31/495;A61K47/48;A61P35/00 |
主分类号 |
A61K31/495 |
| 代理机构 |
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