A PRODUCING METHOD FOR CEPHALOSPORIN C USING A GLYCEROL

摘要

PURPOSE: A method for preparing novel cephalosporin C is provided to enhance productivity of cephalogporin C and to reduce purification cost. CONSTITUTION: A method for preparing cephalosporin C using microorganism comprises a step of culturing Acremonium chrysogenum in a medium containing 2-6% glycerol as a carbon source. The medium further contains glucose as a carbon source. The medium contains 2-6% glycerol, 3-7% corn liquid, 0.6-1.0% of (NH_4)_2SO_4, 0.1-0.5% of KH_2PO_4, 0.3-0.7% of K_2HPO_4, 0.3-0.7% of DL-methionine, 0.2-0.6% of trace element solution.