发明名称 |
COMPOSITIONS AND METHODS FOR MODULATING D1-D2 DOPAMINE RECEPTOR INTERACTION AND FUNCTION |
摘要 |
The present invention provides for prevention and/or treatment of neurological or neuropsychiatric disorders involving abnormal D1-D2 dopamine receptor coupling and/or activation. Methods and agents are provided for modulating dopamine receptor function arising from D1-D2 coupling and/or activation. Agents of the present invention include fragments of D2 receptor or D1 receptor that can disrupt D1-D2 coupling. |
申请公布号 |
EP2294081(A1) |
申请公布日期 |
2011.03.16 |
申请号 |
EP20090761218 |
申请日期 |
2009.06.12 |
申请人 |
CENTRE FOR ADDICTION AND MENTAL HEALTH |
发明人 |
LIU, FANG;PEI, LIN |
分类号 |
C07K14/705;A61K38/00;A61K38/20;A61K39/395;A61P25/24;C07K16/28;C07K19/00;C12N15/12 |
主分类号 |
C07K14/705 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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