SELF-INACTIVATING HELPER ADENOVIRUSES FOR THE PRODUCTION OF HIGH-CAPACITY RECOMBINANT ADENOVIRUSES
摘要
The invention relates to reagents and methods for the generation of auto-inactivating helper adenoviruses that allow the development of cell systems for the generation of high-capacity recombinant adenovirus showing a reduced contamination by auxiliary adenoviruses.
申请公布号
EP2295591(A1)
申请公布日期
2011.03.16
申请号
EP20090745870
申请日期
2009.05.13
申请人
PROYECTO DE BIOMEDICINA CIMA, S.L.
发明人
GONZALEZ APARICIO, MANUELA;HERNANDEZ ALCOCEBA, RUBEN;MAULEON MAYORA, MIREN ITSASO