发明名称 Glycosylation engineering of antibodies for improving antibody-dependent cellular cytotoxicity
摘要 The present invention relates to the field glycosylation engineering of proteins. More particular, the present invention is directed to the glycosylation engineering of proteins to provide proteins with improved therapeutic properties, e.g., antibodies, antibody fragments, or a fusion protein that includes a region equivalent to the Fc region of an immunoglobulin, with enhanced Fc-mediated cellular cytotoxicity.
申请公布号 US7906329(B2) 申请公布日期 2011.03.15
申请号 US20030437388 申请日期 2003.05.14
申请人 GLYCART BIOTECHNOLOGY AG 发明人 UMANA PABLO;JEAN-MAIRET JOEL;BAILEY JAMES E
分类号 C12N5/10;C12N15/09;A61K39/395;A61P35/00;C07H21/04;C07K16/00;C07K16/28;C07K16/30;C12N1/15;C12N1/19;C12N1/21;C12P21/00;C12P21/08 主分类号 C12N5/10
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