| 发明名称 |
METHODS FOR PRODUCING PREPARATIONS OF RECOMBINANT AAV VIRIONS SUBSTANTIALLY FREE OF EMPTY CAPSIDS |
| 摘要 |
Methods for separating AAV empty capsids from mixtures of AAV vector particles and AAV empty capsids are described. The methods use column chromatography techniques and provide for commercially viable levels of recombinant AAV virions. |
| 申请公布号 |
PT1625210(E) |
申请公布日期 |
2011.03.15 |
| 申请号 |
PT20040776068T |
申请日期 |
2004.05.21 |
| 申请人 |
GENZYME CORPORATION |
发明人 |
GUANG QU;JOHN FRASER WRIGHT |
| 分类号 |
C12N7/02;B01D15/00;B01D15/04;C02F1/42;C12N;C12N15/86;C12N15/864 |
主分类号 |
C12N7/02 |
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