THERAPEUTIC USAGE OF COPA3 PEPTIDE ANALOGUE ISOLATED FROM COPRIS TRIPARTITUS FOR C. DIFFICILE-PSEUDOMEMBRANOUS COLITIS AND GENERAL GUT INFLAMMATION

摘要

PURPOSE: A composition containing coprisin peptide derivative CopA3(HL) for treating Pseudomembranous colitis is provided to prevent antibiotics effect to helpful microbes such as Bifidobacterium and Lactobacillus. CONSTITUTION: A composition for treating Pseudomembranous colitis contains coprisin peptide derivative CopA3(HL) as an active ingredient. The coprisin peptide derivative CopA3(HL) has an amino acid sequence(L-L-C-I-A-L-R-K-K). The coprisin peptide derivative suppresses Clostrdium difficile in the large intestine. The coprisin peptide derivative CopA3(HL) is D-type.