MICROORGANISM PRODUCING O-ACETYL-HOMOSERINE AND METHOD OF PRODUCING O-ACETYL-HOMOSERINE USING THE SAME

摘要

PROBLEM TO BE SOLVED: To provide a microorganism strain capable of producing L-methionine precursor O-acetyl homoserine in high yield and a method of producing O-acetyl homoserine using the same.

SOLUTION: The microorganism strain is a strain of Escherichia sp. in which an acetyl-CoA synthase gene (acs) and/or a pantothenate kinase gene (coaA) encoding a pantothenate kinase in which feedback inhibition by CoA accumulation is released is introduced and enhanced.

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