发明名称 HISTONE DEACETYLASE INHIBITORS AND USES THEREOF
摘要 Provided herein is a compound of Formula I: wherein R1 and R2 are as disclosed herein, and including reduced forms and dehydration products, and salts thereof. Also provided are compositions, including pharmaceutical compositions, methods of inhibiting histone deacetylase, methods of increasing histone deacetylase-controlled gene expression in a cell, methods of treating a disease associated with increased histone deacetylase activity, methods of inhibiting growth of a cancer cell, and methods of treating cancer in a subject that comprise a compound of Formula I.
申请公布号 US2011060021(A1) 申请公布日期 2011.03.10
申请号 US20100859656 申请日期 2010.08.19
申请人 CHENG YIQIANG;WANG CHENG 发明人 CHENG YIQIANG;WANG CHENG
分类号 A61K31/4178;A61K31/395;A61K31/404;A61P35/00;A61P35/02;C07D513/02;C12N5/09;C12N9/78 主分类号 A61K31/4178
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