摘要 |
<p>This invention relates, e.g., to a method for promoting CNS axon regeneration, comprising (1) inhibiting the expression or activity in a neuron of one or more of the members of the Krüppel-like transcription factor (KLF) family that suppress axon growth (e.g., KLF 1, 2, 3, 4, 5, 9, 12, 13, 14, 15 and/or 16), and/or (2) stimulating the expression or activity in a neuron of one or more of the members of the KLF family that promote axon growth (e.g., KLF 6 and/or 7).</p> |
申请人 |
UNIVERSITY OF MIAMI;GOLDBERG, JEFFREY L.;LEMMON, VANCE P.;BIXBY, JOHN;MOORE, DARCIE;BLACKMORE, MURRAY |
发明人 |
GOLDBERG, JEFFREY L.;LEMMON, VANCE P.;BIXBY, JOHN;MOORE, DARCIE;BLACKMORE, MURRAY |