发明名称 |
APPARATUS AND METHODS FOR VISUAL DEMONSTRATION OF DENTAL EROSION ON SIMULATED DENTAL MATERIALS |
摘要 |
<p>Comparative effectiveness of various oral care products such as dentifrices on preventing dental erosion may be demonstrated using simulated enamel. A substrate is prepared. A mineral layer to simulate dental enamel is nucleated by solution growth on the substrate surface. Alternatively, the mineral layer may be nucleated on a template comprising a self-assembled monolayer formed on a gold layer deposited on the substrate surface. The mineral layer may comprise a homogeneous layer of hydroxyapatite or a thin veneer of hydroxyapatite on a layer of amorphous calcium phosphate. The simulated enamel is then optionally treated with an oral care product and subjected to an acid challenge. The amount of mineral layer remaining after the acid challenge dramatically illustrates the effectiveness or non-effectiveness of the oral care product at preventing dental erosion.</p> |
申请公布号 |
CA2773162(A1) |
申请公布日期 |
2011.03.10 |
申请号 |
CA20102773162 |
申请日期 |
2010.09.01 |
申请人 |
THE PROCTER & GAMBLE COMPANY |
发明人 |
DRAKE, PHILLIP ASA;PENG, RUZHAN;DECKNER, GEORGE ENDEL |
分类号 |
A61K6/033 |
主分类号 |
A61K6/033 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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