GLYCERALDEHYDE-3-PHOSPHATE DEHYDROGENASE AND PHOSPHOGLYCERATE MUTASE PROMOTERS FOR GENE EXPRESSION IN OLEAGINOUS YEAST

摘要

Promoter regions associated with the Yarrowia lipolytica glyceraldehyde-3-phosphate dehydrogenase (gpd) gene have been found to be particularly effective for the expression of heterologous genes in yeast. Promoter regions of a Yarrowia gpd gene shown to drive high-level expression of genes involved in the production of omega-3 and omega-6 fatty acids are disclosed.