| 发明名称 |
MODULATION OF APOLIPOPROTEIN C-III EXPRESSION |
| 摘要 |
Compounds, compositions and methods are provided for modulating the expression of apolipoprotein C-III. The compositions comprise oligonucleotides, targeted to nucleic acid encoding apolipoprotein C-III. Methods of using these compounds for modulation of apolipoprotein C-III expression and for diagnosis and treatment of disease associated with expression of apolipoprotein C-III are provided |
| 申请公布号 |
US2011060030(A1) |
申请公布日期 |
2011.03.10 |
| 申请号 |
US20100781479 |
申请日期 |
2010.05.17 |
| 申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
CROOKE ROSANNE M.;GRAHAM MARK J.;LEMONIDIS KRISTINA M.;DOBIE KENNETH W. |
| 分类号 |
A61K31/7088;A61K38/00;A61P3/00;A61P3/04;A61P3/06;A61P3/10;A61P9/00;A61P9/10;C07H21/00;C12N5/071;C12N15/113;C12Q1/68 |
主分类号 |
A61K31/7088 |
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