发明名称 |
ANTIBODIES SPECIFIC OF THE BETA-AMYLOID PEPTIDES AND THEIR USES AS DIAGNOSTIC AGENTS OR DRUGS |
摘要 |
The present invention relates to a monoclonal antibody which specifically binds to the N-terminal region of A&bgr;8-x peptide, x being comprised from 11 to 42, and recognises neither A&bgr;1-40 nor A&bgr;1-42 and which presents a high affinity with respect to A&bgr;8-x peptide, such as determined by an immunological complex formation between the monoclonal antibody and the peptide A&bgr;8-x.
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申请公布号 |
US2011059092(A1) |
申请公布日期 |
2011.03.10 |
申请号 |
US20080740217 |
申请日期 |
2008.10.24 |
申请人 |
INNOGENETICS NV;SANOFI-AVENTIS |
发明人 |
VANMECHELEN EUGEEN;GROGNET PIERRE;SERGEANT NICOLAS;GOMPEL MARIE;DELACOURTE ANDRE;BUEE LUC;PRADIER LAURENT;BLANCHARD-BREGEON VERONIQUE |
分类号 |
A61K39/395;A61K39/00;A61P25/28;C07K7/00;C07K16/18;C12N5/16;C12N9/96;G01N33/53;G01N33/566 |
主分类号 |
A61K39/395 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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