发明名称 PROCESSES FOR ISOLATION AND PURIFICATION OF ENFUMAFUNGIN
摘要 The present disclosure relates to processes useful in the isolation and purification of enfumafungin, which is classified as a triterpene glycoside antifungal compound and acts as a glucan synthase inhibitor. Enfumafungin has application in the treatment of conditions caused by fungal infection and is also useful as an intermediate in the preparation of other compounds useful as antifungal agents and/or inhibitors of (1,3)-ß-D-glucan synthesis.
申请公布号 WO2011028654(A1) 申请公布日期 2011.03.10
申请号 WO2010US47104 申请日期 2010.08.30
申请人 MERCK SHARP & DOHME CORP.;POLLARD, JENNIFER, M.;CHMIELOWSKI, REBECCA, A.;DEITRICH, LISA, M.;GAILLIOT, FRANCIS, P.;GOKLEN, KENT 发明人 POLLARD, JENNIFER, M.;CHMIELOWSKI, REBECCA, A.;DEITRICH, LISA, M.;GAILLIOT, FRANCIS, P.;GOKLEN, KENT
分类号 A61K31/497 主分类号 A61K31/497
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