发明名称 PHARMACEUTICAL COMPOSITION FOR THE ADMINISTRATION BY INJECTION BASED ON QUADRIVALENT PLATINUM AND CYCLODEXTRIN
摘要 A pharmaceutical composition for administration By injection, comprising a mixture of platinum complex of general formula (I), wherein A and A' independently of one another are an NHgroup or an amino or diamino group containing 1 to 18 carBon atoms, B and B' independently of one another are a halogen atom or a hydroxy group or are an -O-C(O)-R or -O-C(O)-R' group wherein R and R' independently of one another are a hydrogen atom or an alkyl, alkenyl, aryl, aralkyl, alkylamino or alkoxy group, which groups contain 1 to 10 carBon atoms, or functional derivatives of these groups, X and X' independently of one another are a halogen atom or a monocarBoxylate group containing 1 to 20 carBon atoms, or X and X' together form a dicarBoxylate group containing 2 to 20 carBon atoms, and of at least one cyclodextrin and/or at least one cyclodextrin derivative, and optionally of at least one pharmaceutically acceptaBle excipient., (I)
申请公布号 UA93715(C2) 申请公布日期 2011.03.10
申请号 UA20080014646 申请日期 2007.06.20
申请人 PLIVA-LACHEMA A.S. 发明人 FRANC ALES;SOVA PETR
分类号 A61K47/40;A61K31/282;A61K47/48 主分类号 A61K47/40
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