METHOD FOR TREATING INFECTIOUS BACTERIAL DISEASE WITH ANTI-LACTONE SIGNAL MOLECULE ANTIBODY OR ANTI-LACTONE-DERIVED SIGNAL MOLECULE ANTIBODY

摘要

PROBLEM TO BE SOLVED: To provide a method for controlling the virulence of infectious bacteria by regulating the extra-cellular concentration of bacterial cell signaling molecules. SOLUTION: The method for treating bacterial infectious diseases includes: isolation of a bacterial lactone signal molecule or lactone-derived signal molecule in a sample from the subject, and using the bacterial lactone signal molecule to screen a population of specific binding molecules for an anti-bacterial specific binding molecule to identify a specific binding molecule that specifically binds to the signal molecule, and administering the specific binding molecule so identified to a patient in need thereof. COPYRIGHT: (C)2011,JPO&INPIT