发明名称 |
MODULATION OF FACTOR 9 EXPRESSION |
摘要 |
Disclosed herein are antisense compounds and methods for decreasing Factor 9 and increasing clotting time in an individual in need thereof. Examples of disease conditions that can be ameliorated with the administration of antisense compounds targeted to Factor 9 include thrombosis, embolism, thromoboembolism such as deep vein thrombosis, pulmonary embolism, myocardial infarction, and stroke.
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申请公布号 |
US2011059895(A1) |
申请公布日期 |
2011.03.10 |
申请号 |
US20080742076 |
申请日期 |
2008.11.05 |
申请人 |
ISIS PHARMACEUTICALS, INC. |
发明人 |
FREIER SUSAN M.;MONIA BRETT P.;ZHANG HONG;ZHAO CHENGUANG |
分类号 |
A61K38/16;A61K31/7088;A61P7/02;A61P9/00;A61P9/10;C07H21/00;C07H21/04;C12N15/113 |
主分类号 |
A61K38/16 |
代理机构 |
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代理人 |
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主权项 |
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地址 |
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