发明名称 MODULATION OF FACTOR 9 EXPRESSION
摘要 Disclosed herein are antisense compounds and methods for decreasing Factor 9 and increasing clotting time in an individual in need thereof. Examples of disease conditions that can be ameliorated with the administration of antisense compounds targeted to Factor 9 include thrombosis, embolism, thromoboembolism such as deep vein thrombosis, pulmonary embolism, myocardial infarction, and stroke.
申请公布号 US2011059895(A1) 申请公布日期 2011.03.10
申请号 US20080742076 申请日期 2008.11.05
申请人 ISIS PHARMACEUTICALS, INC. 发明人 FREIER SUSAN M.;MONIA BRETT P.;ZHANG HONG;ZHAO CHENGUANG
分类号 A61K38/16;A61K31/7088;A61P7/02;A61P9/00;A61P9/10;C07H21/00;C07H21/04;C12N15/113 主分类号 A61K38/16
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