| 发明名称 |
PEPTIDES THAT BLOCK THE BINDING OF IgG TO FcRn |
| 摘要 |
The invention relates to peptides which bind to human FcRn and inhibit binding of the Fc portion of an IgG to an FcRn, thereby modulating serum IgG levels. The disclosed compositions and methods may be used for example, in treating autoimmune diseases and inflammatory disorders. The invention also relates to methods of using and methods of making the peptides of the invention.
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| 申请公布号 |
US2011059889(A1) |
申请公布日期 |
2011.03.10 |
| 申请号 |
US20090641844 |
申请日期 |
2009.12.18 |
| 申请人 |
SYNTONIX PHARMACEUTICALS, INC. |
发明人 |
MEZO ADAM R.;MCDONNELL KEVIN A.;TAN HEHIR CRISTINA A.;CASTRO ALFREDO |
| 分类号 |
A61K38/12;A61K38/16;A61P1/04;A61P3/10;A61P17/06;A61P29/00;A61P35/00;A61P37/06;C07K1/22;C07K7/52;C07K7/64;C07K14/00;C07K14/76;C07K14/79;C07K19/00;G01N33/53 |
主分类号 |
A61K38/12 |
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