摘要 |
Disclosed herein, in certain embodiments, is an HC·HA complex comprising hyaluronan and a heavy chain of IaI, wherein the transfer of the heavy chain of IaI is catalyzed by TSG-6. Further disclosed herein, in certain embodiments, is an HC·HA complex comprising hyaluronan and a heavy chain of IaI, wherein the transfer of the heavy chain of IaI is catalyzed by the TSG-6 like protein. Additionally, disclosed herein are methods of manufacturing said complex and methods of use thereof |