发明名称 Spirocyclohexane benzocycloalkane acetic acid derivs - - analgesics and antiinflammatories
摘要 <p>The title cpds. of formula (I): where X = Cl, F or lower alkoxy; R = H or straight or branched alkyl (1-4C); n = 2, 3 or 4; are prepd. by the reduction of a ketone gp. in the cycloalkane ring. In an example, 293 mg. 71-chloro-31-oxo spiro-(cyclohexane-1,11-indane)-5-acetic acid was treated with 3 ml. ethylene glycol, 180 mg. KOH and 0.135 ml. hydrazine hydrate to give 85% yield of (I); X = Cl; R = H; n = 2.</p>
申请公布号 FR2101128(A1) 申请公布日期 1972.03.31
申请号 FR19700031189 申请日期 1970.08.26
申请人 ROUSSEL UCLAFF 发明人
分类号 C07C49/697;C07C57/62;C07C59/88;(IPC1-7):61K27/00;07C63/00;07C65/00;07C69/00 主分类号 C07C49/697
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